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High platelets is a condition when the number of platelets in the body exceeds the normal number. In adults, the normal limit for the platelet count is 150,000–400,000 per microliter of blood. High platelets can be caused by a variety of conditions
Platelets are blood cells that play a role in the blood clotting process. The role of platelets is very important, especially to stop bleeding when there is an injury or rupture of a blood vessel.
However, if the platelet count is too high (thrombocytosis) it can cause excessive blood clots or clots.
These blood clots can block blood vessels and block blood flow to important organs, such as the brain, heart, and lungs. This condition can trigger dangerous diseases, such as stroke, heart disease, and pulmonary embolism.
Conditions That Can Cause High Platelets
The following are some of the factors that can cause high platelets:
1. Network damage
Damage to body tissues can trigger an increase in the number of platelets. Tissue damage can result from injury, injury, or postoperative conditions.
High platelets due to this condition normally occur as the body's natural mechanism to prevent fatal bleeding and help the body recover from damage.
2. Blood loss
When the body is injured and bleeding, the bone marrow will respond by producing more red blood cells and platelets. The platelet count will be high for some time to stop the bleeding. When the bleeding has stopped, the platelet count will drop and return to normal.
Infection is one of the things that often causes an increase in the number of platelets. The increase in the number of platelets is thought to be due to the influence of cytokine hormones that act as part of the body's defense against infection.
Generally, this condition does not cause symptoms and the platelet count will return to normal once the infection is treated properly.
Similar to infection, inflammation can also cause the number of platelets to increase due to an increase in the production of cytokine proteins. This can occur in people with certain inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease.
Cancer can cause a high platelet count by causing damage to surrounding tissues and affecting the immune system's response to stimulating the bone marrow to produce platelets.
6. Bone marrow disorders
High platelet counts can occur due to bone marrow disorders or diseases that stimulate the formation of excessive platelets in the bone marrow, such as myeloproliferative disease, leukemia or blood cancer, and polycythymia vera.
7. Genetic factors
An increased platelet count can also be caused by a genetic disorder that makes the bone marrow produce too many platelets. In medical terms, this condition is called primary thrombocythemia or primary thrombocythemia.
8. Side effects of certain drugs
A high platelet count can sometimes also be caused by a side effect of certain medications, such as corticosteroids and rituximab. These drugs can usually also be used to treat conditions that decrease the number of platelets due to immune thrombocytopenia (ITP).
Generally, these side effects are temporary and platelets will return to normal when the drug is stopped.
High platelets are often asymptomatic and are only detected when you undergo a medical examination. However, in certain cases, high platelets can also cause several symptoms, such as headaches, chest pain, dizziness, weakness, frequent bruising, nosebleeds, and numbness or tingling in the feet or hands.
To evaluate the platelet count, you can see a doctor. The doctor will perform a physical examination and recommend a complete blood test. If the results of the examination show that you have a high platelet count, the doctor will provide treatment according to the cause.