Knowing mRNA vaccines and how they work

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Knowing mRNA vaccines and how they work
Knowing mRNA vaccines and how they work

mRNA vaccine is a type of vaccine developed to treat or prevent the spread of COVID-19. This vaccine is a new type of vaccine whose content is different from other types of vaccines

Vaccines usually contain a virus or disease-causing germ that has been weakened or killed. However, mRNA (messenger RNA) vaccines are vaccines with new technology or variants.

Get to know mRNA vaccines and how they work - Alodokter

mRNA vaccines do not use weakened or killed viruses or germs, but components of genetic material that are engineered to resemble certain germs or viruses.Thus, this vaccine can trigger an immune reaction like viruses and germs that are weakened in ordinary vaccines.

This type of vaccine is currently being developed as a Corona virus vaccine to trigger the body's immune response to fight COVID-19.

How mRNA Vaccines Work

The mRNA vaccine is given by injection into a muscle, usually in the upper arm.

After entering the body, the mRNA from the vaccine captured by immune cells will direct these cells to produce spike proteins. This protein is a protein that makes up part of the surface of the Corona virus.

Furthermore, after the body's immune cells recognize these components, the immune system will produce specific antibodies to fight the Corona virus.

By giving the mRNA vaccine, it is hoped that the body will more quickly detect and destroy the Corona virus when you are exposed to the virus, so that you can avoid COVID-19.After giving this vaccine, you can undergo serological tests to determine whether your body has produced an immune reaction to the Corona virus. However, this test is not mandatory for everyone.

Before being used as a vaccine for COVID-19, mRNA vaccine technology has been extensively studied for its effectiveness against flu, Zika, rabies, and cytomegalovirus (CMV). This vaccine is also used by researchers to trigger an immune system reaction against tumor cells.

Advantages and Disadvantages of mRNA Vaccines

mRNA vaccines have advantages and disadvantages. The advantages of mRNA vaccines are:

  • This type of vaccine is easy to make because it can be developed in the laboratory using readily available materials.
  • The price is cheap.
  • mRNA vaccine does not trigger infection because it does not contain viruses or bacteria.
  • Research so far shows that the mRNA vaccine is safe for the elderly.

On the other hand, mRNA vaccines also have some disadvantages, namely:

  • This vaccine must be stored at a very cold temperature of -70° Celsius or lower, requiring a special refrigerated container. This can be a challenge for countries that do not have such equipment, especially developing countries.
  • Vaccination needs to be given more than once.
  • The mRNA vaccine can only be given to the 16 year old age group and over.

mRNA Vaccine Safety

Some time ago there were rumors that mRNA vaccines can damage human DNA, but this has not been proven true.

The mRNA vaccine has no effect on the genetic components or DNA of the human body, because the body's immune cells will get rid of the components of the mRNA vaccine as soon as the vaccine works and successfully create immunity to the disease.

However, just like other vaccines, mRNA vaccines can also cause some side effects, such as:

  • Pain, swelling, or redness at the injection site
  • Feeling tired
  • Headache
  • Muscle pain
  • Joint pain
  • Chills or fever
  • Nausea

While the COVID-19 pandemic is still ongoing, don't forget to always apply he alth protocols wherever you are, especially when doing activities outside the home.

If you have a history of contact with a COVID-19 patient or experience symptoms of cough, fever, hoarseness, anosmia, or shortness of breath, immediately contact the nearest he alth care facility to get a COVID-19 examination.

If you want to know more about mRNA vaccines, you can chat directly with a doctor or make an appointment with a doctor on the ALODOKTER application.

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