Diphencyprone (DPCP) - Benefits, dosage and side effects

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Diphencyprone (DPCP) - Benefits, dosage and side effects
Diphencyprone (DPCP) - Benefits, dosage and side effects

Diphencyprone (DPCP) is a drug that can be used to treat alopecia areata. This drug has a liquid dosage form that will be applied to the bald area. Diphencyprone can only be given by a doctor

When used to treat alopecia areata, diphencyprone will trigger allergic reactions, such as contact dermatitis. Through this mechanism, diphencyprone is expected to stimulate hair growth.

Diphencyprone (DPCP) - allodokter
Diphencyprone (DPCP) - allodokter

In addition to treating baldness due to alopecia areata, diphencyprone can also be used in the treatment of warts due to infection with the HPV (human papillomavirus) virus and melanoma on the skin.

Diphencyprone is usually only used if the patient's condition cannot be managed with other treatment methods.

Diphencyprone (DPCP) trademark: -

What is Diphencyprone (DPCP)?

Class Immunotherapy
Categories Prescription drugs
Benefits Stimulates hair growth
Used by Adults and children
Diphencyprone for pregnant and lactating mothers Category N: Uncategorized

Diphencyprone is not recommended for use in women who are pregnant, breastfeeding, or planning a pregnancy.

This is because the effectiveness and side effects of this drug have not been studied in pregnant women. It is also not known whether diphencyprone can affect fertility.

Medicine form Liquid

Warning Before Using Diphencyprone (DPCP):

  • Do not use diphencyprone if you have a history of allergies to this drug or other immunotherapy drugs.
  • There is no known safety of diphencyprone in pregnant women, nursing mothers, or women who are planning a pregnancy. Avoid using this drug in these conditions.
  • Tell your doctor about all your medical history and current medications.
  • Avoid exposure to direct sunlight, and do not use ultraviolet lamps (sunbed) to darken the skin (tanning) while using diphencyprone.
  • Patients need to be informed of the stages of therapy and possible complaints, such as itching or redness of the skin while undergoing therapy with diphencyprone.
  • Be careful when using accessories, including hats or cloths, to protect yourself from the sun while undergoing therapy with diphencyprone. This is because the chemicals contained in the drug can stick to the surface of the clothes.
  • See a doctor immediately if side effects occur after using diphencyprone.

Dosage and Instructions for Use of Diphencyprone (DPCP)

Diphencyprone can generally be given to adults and children. Keep in mind, diphencyprone is only given by a doctor and should not be used carelessly.

The dose of diphencyprone will be determined based on the type of skin disorder to be treated, the severity of the condition, and response to therapy. Diphencyprone will cause an allergic reaction characterized by the appearance of a red and itchy rash that will last for 36–48 hours.

The stages that the patient will undergo when using diphencyprone are as follows:

Stage 1

Diphencyprone in strong doses (generally with a concentration of 2%) is applied to a small area of the skin, usually on the upper arm. Allergic reactions will generally appear within 2-3 days after the first use.

If no allergic reaction occurs, a lower dose of diphencyprone (0.1%) will be applied to the same area 2 weeks later and will be repeated every 2 weeks until an allergic skin reaction occurs.

Stage 2

If an allergic reaction has occurred, the next step is to determine the right dose to cause the desired allergic reaction in the skin. The doctor will apply a very low dose of the drug (usually at a concentration of 0.001%) on a small area of the skin.

The dose given will be increased every week until the desired reaction occurs on the skin.

Stage 3

After knowing the right dose, diphencyprone will be applied to the problematic skin every 1-2 weeks.

The duration of using diphencyprone varies for each patient, depending on how quickly the patient's body responds to the drug, and the severity of the condition. Generally, diphencyprone is given for 6–8 months.

Diphencyprone administration will be discontinued when the condition being treated has healed. However, in some people with alopecia areata, treatment with diphencyprone may need to be repeated if baldness occurs again.

How to Use Diphencyprone (DPCP) Correctly

Diphencyprone should only be given by a doctor or medical officer under the supervision of a doctor. Follow the doctor's instructions when undergoing therapy with diphencyprone.

Skin surface needs to be cleaned and dried before starting the treatment procedure. Diphencyprone administration generally takes about 10-15 minutes.

During the use of the drug, protect the skin that has been smeared with diphencyprone from direct sunlight for about 6-8 hours. For example, if you are using a diphencyprone to treat head baldness, it is recommended that you cover your head when you are outdoors, for example with a hat.

Avoid touching the skin that has been smeared with diphencyprone for 24 hours. If touched, wash hands immediately. After 6–24 hours, wash the skin that was smeared with diphencyprone.

Sometimes an allergic reaction caused by this drug can occur excessively and cause complications. Therefore, the doctor may prescribe a corticosteroid ointment with a very strong level to anticipate the occurrence of an allergic reaction. The doctor will usually give directions and explanations about the use of this additional drug.

Diphencyprone should be stored in a dark glass bottle, placed in a closed place, protected from direct sunlight, and out of reach of children.

Side Effects and Dangers of Diphencyprone (DPCP)

Diphencyprone can cause side effects such as:

  • Scars due to inflammation of the skin
  • Eczema that is too severe, characterized by skin redness, crusting, itching, blistering, and discharge of pus
  • Skin changes color to blackish (hyperpigmentation) or pale white (hypopigmentation)

In addition, a number of other, more serious side effects can also arise from diphencyprone, including:

  • Eczema that spreads all over the body
  • Vitiligo
  • Enlarged lymph nodes
  • Pompholyx
  • Other allergic reactions, can be flu-like complaints or erythema multiforme
  • Urticaria
  • Headache
  • Heart pounding

See your doctor as soon as possible if you experience any of the side effects mentioned above during treatment with diphencyprone.