Antalgin - Benefits, dosage and side effects

Table of contents:

Antalgin - Benefits, dosage and side effects
Antalgin - Benefits, dosage and side effects

Antalgin is useful to relieve pain and relieve fever. This drug can also be used to treat headaches, toothaches, and menstrual pain. Antalgin is available in tablet and injection form

Antalgin contains metamizole, which is also known as metampirone or dipyrone. How metamizole works in relieving pain is not known with certainty. However, several studies have shown that metamizole inhibits the action of the hormone prostaglandin, so that pain and inflammation can be reduced.

Antalgin - allodokter
Antalgin - allodokter

Antalgin is available in several forms, namely Antalgin tablets 500 mg, Antalgin caplets 500 mg, and Antalgin injections 250 mg/ml.

What is Antalgin

Active ingredients Metamizole
Class Analgesics or pain relievers from the class of non-steroidal anti-inflammatory drugs (NSAIDs) Antipyretics (fever-reducing drugs)
Categories Prescription drugs
Benefits Relieve pain and relieve fever
Consumed by Adults and children
Antalgin for pregnant and lactating women Category C (in the first and second trimester): Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus.

Category D (in the third trimester): There is positive evidence of risks to the human fetus, but the benefits may outweigh the risks, for example in dealing with life-threatening situations.

Metamizole can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor.

Medicine form Tablets, caplets and injections

Warning Before Using Antalgin

  • Tell your doctor about any allergies you have. Antalgin should not be given to patients who are allergic to this drug or to metamizole.
  • Tell your doctor if you have or have had blood disorders, G6PD deficiency, spinal cord disorders, porphyria, low blood pressure, dehydration, asthma, stomach ulcers, duodenal ulcers, heart disease, liver or kidney disorders.
  • Do not consume alcoholic beverages while you are on treatment with Antalgin.
  • Do not drive a motorized vehicle, operate machinery, or engage in activities that require alertness after taking Antalgin, as metamizole can cause difficulty concentrating.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements or herbal products.
  • See your doctor immediately if you experience an allergic drug reaction, overdose, or serious side effects after using Antalgin.

Dosage and Rules for Use of Antalgin

Antalgin dosage to relieve pain and fever based on the patient's age and the dosage form of the drug is:

  • Antalgin tablets or caplets

    Adults: 500–1,000 mg taken 3–4 times a day, maximum treatment time is 4–5 days. The maximum dose is 4,000 mg/day.

    Children over 3 months: The dose is determined based on the patient's weight. The recommended dose is 8–16 mg/kgBB, taken 3–4 times a day.

  • Antalgin injection

    Adult: 1,000 mg given up to 4 times a day or 2,500 mg given 2 times a day. The dose can be readjusted based on the patient's condition and response to treatment. The maximum dose is 5,000 mg/day.

    Children aged over 3 months: The dose is determined based on the patient's weight.

How to Use Antalgin Correctly

Follow the doctor's advice and read the information on the Antalgin package before using it.

Injectable antalgin can be given through a vein (intravenous/IV) or injected into a muscle (intramuscular/IM) by a doctor or he alth worker under the supervision of a doctor at the hospital.

Take Antalgin tablets or caplets after meals. Swallow the medicine whole with the help of a glass of water. Do not increase or decrease the dose or extend the duration of use of the drug without consulting your doctor first.

Store Antalgin at room temperature, in a dry place, and away from direct sunlight. Keep medicine out of reach of children.

Antalgin Interaction with Other Drugs

Interaction effects that can occur if Antalgin is used with certain drugs are:

  • Increased risk of thrombocytopenia when used with blood thinners
  • Increased risk of severe hypothermia when used with chlorpromazine and phenothiazine
  • Increased risk of side effects or Antalgin poisoning if used with tricyclic antidepressants, MAOI drugs, birth control pills, or allopurinol
  • Reduced effectiveness of Antalgin when used with barbiturates, glutethimide, or phenylbutazone
  • Increased risk of side effects from diabetes medications, sulfonamide antibiotics, or phenytoin
  • Increased damaging effect on blood cells when used with methotrexate
  • Decreased effectiveness of ciclosporin or bupropion

Side Effects and Dangers of Antalgin

Side effects that may occur after using drugs containing metamizole are:

  • Nausea
  • Vomiting
  • stomach ache
  • heartburn
  • Dizziness or vertigo
  • Skin rash

Check with your doctor if these side effects don't go away or get worse. See your doctor immediately if you have an allergic reaction to the drug or a more serious side effect, such as chest pain, irregular heartbeat, red urine, very reduced or absent urine output, or jaundice.