Table of contents:
- What is Antitetanus
- Warning Before Using Antitetanus
- Dosage and Rules for Use of Antitetanus
- How to Use Antitetanus Correctly
- Interaction of Antitetanus with Other Drugs
- Side Effects and Dangers of Antitetanus
Antitetanus or tetanus immune globulin (TIG) is used to prevent or treat tetanus infection. Tetanus is caused by infection with the bacterium Clostridium tetani. Tetanus will cause severe muscle spasms which can be fatal
Antietanus contains large amounts of immunoglobulin or tetanus antibodies. The tetanus antibodies are derived from human blood plasma that has been screened and the virus has been inactivated.
Antietanus works by supplying antibodies that the body needs to protect itself from tetanus infection (passive protection).This passive protection will last in the body until finally the body can create its own antibodies that can fight against tetanus. Antitetanus trademark: Tetagam P
What is Antitetanus
|Benefits||Prevent or treat tetanus|
|Used by||Adults and children|
|Antitetanus for pregnant and lactating mothers||Category C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women.
Drugs should only be used if the expected benefit outweighs the risk to the fetus.
It is not yet known that antitetanus can be absorbed into breast milk or not. Consult your doctor first before getting vaccinated with anti-tetanus serum.
Warning Before Using Antitetanus
Pay attention to the following points before getting antitetanus:
- Tell your doctor about any allergies you have.
- Tell your doctor if you have or have had a blood disorder, blood clotting disorder, or low platelet count (thrombocytopenia).
- Tell your doctor if you are taking any other medications, supplements, or herbal products.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- Tell your doctor if you have received a live vaccine in the last 3 months or plan to immunize with a live vaccine, such as the typhoid vaccine.
- Tell your doctor if you have recently received antitetanus while undergoing laboratory tests, as this medicine may affect test results.
- Go to the doctor immediately if you experience an allergic reaction to the drug after the antitetanus injection.
Dosage and Rules for Use of Antitetanus
The dose of antitetanus will be adjusted according to the patient's age, condition, and response to the drug. Here are the general doses of antitetanus by purpose:
Goal: Preventing tetanus (passive protection)
- Adults and children: The starting dose is 250 units. The dose can be increased to 500 units after 24 hours.
Purpose: Treating tetanus
- Adults and children: 3000-6000 units injected into some areas.
How to Use Antitetanus Correctly
Antitetanus must be given by a doctor or medical officer under the supervision of a doctor by way of injection into the muscle (intramuscular/IM).
This drug is usually given to people who have not been vaccinated against tetanus. However, people who have been vaccinated can also be given it again, if they have or are at high risk of developing tetanus.
Interaction of Antitetanus with Other Drugs
Antitetanus can reduce the effectiveness of live vaccines, such as measles, influenza, polio, or rotavirus vaccines. In addition, the risk of inflammation increases if antitetanus is used concurrently with ethotoin, fosphenytoin, mephenytoin, or phenytoin
Side Effects and Dangers of Antitetanus
The following side effects can occur after receiving antitetanus:
- Pain, swelling, or soreness at the injection site
- Joint pain
Consult a doctor if these side effects do not subside or are getting worse. Immediately see a doctor if you experience an allergic reaction, which can be characterized by swelling of the lips and eyelids, an itchy rash, or difficulty breathing, after the antitetanus injection