Hyoscine hydrobromide - Benefits, dosage and side effects

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Hyoscine hydrobromide - Benefits, dosage and side effects
Hyoscine hydrobromide - Benefits, dosage and side effects

Hyoscine hydrobromide or scopolamine hydrobromide is a drug commonly used to prevent and treat motion sickness symptoms, such as nausea, vomiting, and dizziness. Hyoscine hydrobromide is available as tablets, transdermal patches, and injections

Hyoscine hydrobromide belongs to the class of antimuscarinic drugs. This drug is able to block the action of the neurotransmitter acetylcholine on the central nervous system so that it can calm and relax the muscles of the digestive tract.

Hyoscine Hydrobromide - Alodokter
Hyoscine Hydrobromide - Alodokter

With this method, hyoscine hydrobromide can relieve symptoms of motion sickness and nausea and vomiting due to vertigo. In addition, this drug can also be used to treat conditions caused by an overactive digestive tract, such as nausea and vomiting after surgery.

Trademark hyoscine hydribromide: -

What is Hyoscine Hydrobromide

Class Prescription drugs
Categories Antimuscarinic
Benefits Relieve motion sickness
Used by Adults and children
Hyoscine hydrobromide for pregnant and lactating mothers Category C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women.

Drugs should only be used if the expected benefit outweighs the risk to the fetus.

Hyoscine hydrobromide can be absorbed into breast milk, but it is not clear whether this is harmful to the baby. If you are breastfeeding, do not use this medication without telling your doctor first.

Medicine form Tablets, transdermal patches, and injections.

Warning Before Using Hyoscine Hydrobromide

Before using this medicine, you need to pay attention to the following points:

  • Tell your doctor about any allergies you have. Hyoscine hydrobromide should not be used by patients allergic to this drug.
  • Tell your doctor if you have fever, suspected food poisoning, constipation, difficulty urinating, and acid reflux.
  • Tell your doctor if you have kidney disease, liver disease, hyperthyroidism, heart disease, glaucoma, myasthenia gravis, enlarged prostate, epilepsy, or digestive disorders, such as constipation, GERD, or colitis.
  • Do not drive a vehicle or do activities that require alertness after using hyoscine hydrobromide, as this medicine may cause drowsiness or blurred vision.
  • Do not consume alcoholic beverages while undergoing treatment with hyoscine hydrobromide because it can cause excessive drowsiness.
  • Tell your doctor if you are taking any other medications, supplements or herbal products.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • See your doctor immediately if you have an allergic reaction, serious side effects, or overdose after using hyoscine hydrobromide.

Dosage and Instructions for Use of Hyoscine Hydrobromide

The following are the dosages of hyoscine hydrobromide based on the form of the drug:


Condition: Motion sickness

  • Adults: Initial dose 0.15–0.3 mg, taken 20–30 minutes before travel or when nausea occurs during travel, can be repeated every 6 hours if needed. The maximum dose is 0.9 mg per day.
  • Children aged 3–4 years: initial dose of 0.075 mg, taken 20-30 minutes before travel or when nausea begins to travel. Maximum dose 0.15 mg daily.
  • Children aged >4–10 years: 0.075–0.15 mg, taken 20-30 minutes before the trip or when nausea starts on the trip, can be repeated every 6 hours if needed. Maximum dose 0.45 mg daily.
  • Children aged >10 years: 0, 15–0, 30 mg, taken 20–30 minutes before travel or when nausea begins on the way, can be repeated every 6 hours if needed. The maximum dose is 0.9 mg daily.

Transdermal patch

Condition: Motion sickness

  • Adults: apply 1 transdermal patch behind the ear, 4–6 hours before the trip or at night before the trip.

Condition: Nausea and vomiting after surgery

  • Adult: Apply 1 transdermal patch behind the ear the night before surgery or 1 hour before cesarean section. Discard the patch after 1 day of use.


Condition: Motion sickness , nausea, vomiting, and vertigo

  • Adults: 0.2 mg, as a single dose, by IM (intramuscular) or SC (subcutaneous) injection.
  • Children: 0, 006 mg/kgBW, as a single dose, by IM (intramuscular) or SC (subcutaneous) injection.

How to Use Hyoscine Hydrobromide Correctly

Follow the doctor's advice and read the information on the drug packaging label before using hyoscine hydrobromide. Do not reduce or increase the dose without consulting your doctor first.

Hyoscine hydrobromide tablets should be taken 30 minutes before traveling. This medicine can be taken before or after meals. Swallow the tablet whole with the help of a glass of water. Do not crush, split or chew the tablet.

For hyoscine hydrobromide transdermal patch form, do not use the patch on injured or irritated skin. Use the patch behind the ear at night before travel or surgery.

Paste and press the transdermal patch for 30 seconds, so that the medicine adheres properly. Remove the medication after 24 hours or as directed by your doctor. Make sure to remove the old patch first, then apply the new patch. Do not use more than one patch at the same time.

Hyoscine hydrobromide injection will be given by a doctor or medical personnel under the supervision of a doctor. Hyoscine hydrobromide will be injected directly through the muscle (intramuscular / IM), or under the skin (subcutaneous / SC). This drug can also be given by injection into a vein (intravenous/IV).

If you forget to take hyoscine hydrobromide tablets before a trip, it is recommended to take them immediately when symptoms of motion sickness begin to appear. Keep following the dosage and instructions for use and do not double the dose.

Store hyoscine hydrobromide at room temperature and avoid direct sunlight. Keep this medicine out of reach of children.

Interaction of Hyoscine Hydrobromide with Other Drugs

The following are some drug interactions that can occur when hyoscine hydrobromide is used with other drugs:

  • Increased risk of side effects when used with amantadine, quinidine, disopyramide, antihistamines, amitriptyline, salbutamol, ipratropium, tiotropium, chlorpromazine, or clozapine
  • Reduced effect of each drug when used with domperidone or metoclopramide

Side Effects and Dangers of Hyoscine hydrobromide

Some of the side effects that can occur after using hyoscine hydrobromide are:

  • Sleepy
  • Dizzy spinning
  • Blurred vision, sensitivity to light, or itchy eyelids
  • Mouth and
  • Constipation
  • Difficulty urinating
  • Feeling hot or fever

Consult a doctor if the above side effects do not go away or bother you a lot. See a doctor or go to the ER immediately if you experience an allergic drug reaction or any of the following serious side effects:

  • Confusion or hallucinations
  • Can't pee at all
  • The eyes are red and very painful, accompanied by loss of vision
  • Heart rate feels fast for quite a long time