Velpatasvir-Sofosbuvir - Benefits, dosage and side effects

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Velpatasvir-Sofosbuvir - Benefits, dosage and side effects
Velpatasvir-Sofosbuvir - Benefits, dosage and side effects

Velpatasvir-sofosbuvir is a combination antiviral drug used to treat chronic hepatitis C. This drug can be used alone or in combination with ribavirin

Velpatasvir belongs to the class of complex replication inhibitors of the hepatitis C virus (HCV) NS5A nucleotide. Meanwhile, sofosbuvir belongs to the class of HCV NS5B polymerase inhibitors.

Velpatasvir Sofosbuvir - alodokter

The combination of velpatasvir and sofosbuvir will interfere with the work of hepatitis C virus enzymes called NS5A and NS5B, which play a role in viral replication. That way, the number of viruses will be reduced, so that the immune system is better able to fight infection.

Trademarks velpatasvir-sofosbuvir: Epclusa, Myhep All

What is Velpatasvir-Sofosbuvir

Class Prescription drugs
Categories Antiviral medicine
Benefits Treating chronic hepatitis C
Consumed by Adult
Velpatasvir-sofosbuvir for pregnant and lactating women Category N: Not categorized yet.

Velpatasvir-sofosbuvir is not known to be absorbed into breast milk or not. If you are pregnant or breastfeeding, do not use this medicine without consulting your doctor first.

Medicine form film-coated caplets or film-coated tablets

Warning Before Taking Velpatasvir-Sofosbuvir

Velpatasvir-sofosbuvir should only be taken according to a doctor's prescription. Note the following points before taking velpatasvir-sofosbuvir:

  • Tell your doctor about any allergies you have. Velpatasvir-sofosbuvir should not be used by someone who is allergic to this drug.
  • Tell your doctor if you have or are currently suffering from kidney disease, heart disease, diabetes, HIV/AIDS, or liver disease, such as hepatitis B
  • Tell your doctor if you are on dialysis (dialysis).
  • Tell your doctor if you are taking any supplements, herbal products, or medications, including heart medications, anticoagulants, or antacids.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • See your doctor immediately if you experience an allergic reaction to the drug, serious side effects, or an overdose after taking velpatasvir-sofosbuvir.

Dosage and Instructions for Use of Velpatasvir-Sofosbuvir

Velpatasvir-sofosbuvir will be given by the doctor, the dose will be determined according to the patient's condition and body response to treatment.

In general, the dose of velpatasvir-sofosbuvir for adults is 1 tablet or caplet per day. One tablet or caplet contains 100 mg of velpatasvir and 400 mg of sofosbuvir. Treatment is carried out for 12–24 weeks. Treatment can be combined with ribavirin.

How to Take Velpatasvir-Sofosbuvir Correctly

Follow the doctor's advice and read the instructions on the medicine package before taking velpatasvir-sofosbuvir. Do not increase or decrease the dose without consulting your doctor.

Take velpatasvir-sofosbuvir regularly at the same time every day to maximize the effect of the drug.Velpatasvir-sofosbuvir can be taken with or without food. Swallow the medicine whole with the help of a glass of water. Do not split, chew or crush the medicine.

Do not stop taking velpatasvir-sofosbuvir even if your condition has improved, except on doctor's advice. Stopping taking the drug before the prescribed time can increase the risk of an uncontrolled viral infection.

If you forget to take velpatasvir-sofosbuvir, take this drug immediately if the gap between the next consumption schedule is not too close. If the time to take the next dose is near or more than 18 hours after taking the last dose, ignore it and do not double the dose.

Make sure there is a gap of 4 hours before or after taking velpatasvir-sofosbuvir if you are going to take antacids. This is done to ensure that the velpastavir-sofosbuvir that is consumed can work effectively.

Keep velpatasvir-sofosbuvir in a closed container in a cool and dry place. Keep the medicine away from direct sunlight and keep the medicine out of reach of children.

Velpatasvir-Sofosbuvir Interaction with Other Drugs

The effects of drug interactions that can occur if velpatasvir-sofosbuvir is used with certain drugs include:

  • Reduced blood levels of velpatasvir when used with ulcer medications, such as antacids, proton pump inhibitors, or H2 antagonists
  • Significant reduction in blood levels of velpataspir-sofosbuvir when used with, such as rifampicin, phenobarbital, phenytoin, or carbamazepine
  • Increased blood levels of digoxin or rosuvastatin
  • Increased risk of impaired clotting time when used with warfarin
  • Increased risk of severe bradycardia and heart rhythm disturbances of heart block type when used with amiodarone

Side Effects and Dangers of Velpatasvir-Sofosbuvir

There are several side effects that can occur after using velpatasvir-sofosbuvir, namely:

  • Exhaustion
  • Headache
  • Nausea
  • Diarrhea
  • Sleep disorders

Consult a doctor if the side effects mentioned above don't go away or get worse. See a doctor immediately if you have an allergic reaction to the drug or serious side effects, such as:

  • Pain in upper right abdomen
  • Vomiting
  • Loss of appetite
  • Feeling unwell
  • Mental and mood disorders, including depression
  • The eyes and skin look yellowish (jaundice)

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