Colesevelam - Benefits, dosage and side effects

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Colesevelam - Benefits, dosage and side effects
Colesevelam - Benefits, dosage and side effects
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Colesevelam is a drug to lower bad cholesterol or low-density lipoprotein (LDL). This drug can also be used to lower blood sugar levels in people with type 2 diabetes

Colesevelam lowers the amount of bad cholesterol by binding to bile acids, preventing their reabsorption, and expelling them through the digestive tract. That way, the liver will use blood cholesterol to form bile acids, and cholesterol levels will be reduced.

Colesevelam - Alodokter

To make treatment more effective, people with high cholesterol must also adopt a he althy lifestyle, including a low-fat diet and regular exercise.

Colesevelam trademark: -

What is Colesevelam

Class Prescription drugs
Categories Bile acid binder
Benefits Helps lower LDL levels and lower blood sugar levels in people with type 2 diabetes
Consumed by Adult
Colesevelam for pregnant and lactating mothers Category B: Animal studies have not shown any risk to the fetus, but there have been no controlled studies in pregnant women.

Colesevelam is not absorbed into breast milk. However, breastfeeding mothers are advised to consult their doctor before using this drug.

Medicine form Powders and tablets

Warning Before Consuming Colesevelam

Before taking this medicine, you need to pay attention to the following things:

  • Do not use cosevelam if you are allergic to this medicine. Tell your doctor about your history of allergies.
  • Tell your doctor if you have diabetic ketoacidosis, intestinal obstruction, very high triglyceride levels, or pancreatitis due to hypertriglyceridemia. Colesevelam should not be used by this patient.
  • Tell your doctor if you have difficulty swallowing (dysphagia), have or have recently had surgery on the digestive tract, or are deficient in fat-soluble vitamins, such as vitamins A, D, E, K.
  • Colesevelam should not be used on patients under 10 years of age and girls who have not had their periods.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements or herbal products.
  • Immediately see a doctor if there is an allergic reaction to the drug or an overdose after using

Dosage and Instructions for Use Colesevelam

The dose of colesevelam will be determined by the doctor according to the patient's condition and the dosage form of the drug. In general, the following is the dosage of colesevelam in the treatment of high cholesterol or type 2 diabetes mellitus according to the dosage form of the drug.

The dose for adults is 1,875 grams or the equivalent of 3 tablets, 2 times a day. The alternative dose is 3.75 grams or the equivalent of 5 tablets, 1 time a day.

How to Consume Colesevelam Correctly

Follow the doctor's advice and read the information listed on the drug packaging before taking colesevelam. Do not reduce or increase the dose without consulting your doctor first.

Colesevelam can be taken with food. Try to take the medicine at the same time every day for maximum treatment.

Swallow the Colesevelam tablet whole with the help of a glass of water. Do not chew or crush the tablet

Dissolve the colesevelam powder into the drink. This medicine should not be taken in dry form. Consume drinks that have been mixed with drugs until they run out, in order to get the right dose.

If you are taking supplements or other medications, take them at least 4 hours before taking colesevelam.

During treatment with colesevelam, your doctor may ask you to do regular blood tests. Follow the examination schedule that has been determined by the doctor.

If you forget to take Colesevelam, it is recommended to drink it immediately if the gap between the next consumption schedule is not too close. If it's close, ignore it and don't double the dose.

Store the colevelam in a dry place away from direct sunlight. Keep this medicine out of reach of children.

Colesevelam Interactions with Other Drugs

The following are some drug interactions that can occur when colesevelam is used with other drugs:

  • Reduced effect or levels of warfarin in the body
  • Decreased concentration of ciclosporin, phenytoin, glibenclamide, ethinyl estradiol, or norethindrone, in the blood
  • Decreased absorption of vitamins A, D, E and K in the body

Side Effects and Dangers of Colesevelam

Some of the side effects that can occur after consuming colesevelam are:

  • Constipation
  • stomach ache or heartburn
  • Headache
  • Back pain
  • Muscle pain

Consult your doctor if the side effects above do not subside immediately or are getting worse. You need to see a doctor immediately if you experience an allergic reaction to a drug or a more serious side effect, such as:

  • Nausea or vomiting
  • severe stomach ache
  • Difficulty swallowing
  • Easy bruising or unusual bleeding

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