Colestipol - Benefits, dosage and side effects

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Colestipol - Benefits, dosage and side effects
Colestipol - Benefits, dosage and side effects

Colestipol is a drug to lower bad cholesterol or low-density lipoprotein (LDL). By lowering bad cholesterol levels, the risk of heart attacks and strokes can also be lowered

Colestipol is a bile acid sequestrant or bile acid binder. This drug works by removing bile acids from the body, so the liver can produce more bile acids using cholesterol in the blood.

Colestipol - Alodokter
Colestipol - Alodokter

To lower bad cholesterol levels, drug consumption must be combined with he althy lifestyle settings, for example by exercising regularly or reducing foods that are high in fat.

Colestipol trademark: -

What is Colestipol

Class Prescription drugs
Categories Bile acid binder
Benefits Helps lower bad cholesterol levels
Consumed by Adult
Colestipol for pregnant and lactating women Category C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women.

Drugs should only be used if the expected benefit outweighs the risk to the fetus.

It is not yet known whether colestipol can be absorbed into breast milk or not. Breastfeeding mothers are advised to consult a doctor before using this drug.

Medicine form Powders and tablets

Warning Before Taking Colestipol

Before taking this medicine, you need to pay attention to the following things:

  • Do not use colestipol if you are allergic to this drug. Tell your doctor about any allergies you have.
  • Tell your doctor if you have or are currently suffering from constipation, liver disease, difficulty swallowing, thyroid disease, hemorrhoids, blood clotting disorders, gallstones, stomach disease, intestinal obstruction, or kidney disease.
  • Tell your doctor if you have ever had surgery on your stomach, intestines or digestive tract.
  • Tell your doctor before taking colestipol if you have phenylketonuria. Some colestipol products may contain phenylalanine.
  • Colestipol should not be used in patients under 18 years of age.
  • Tell your doctor if you are taking any medications, supplements or herbal products. Colestipol can affect the absorption of folic acid and fat-soluble vitamins, such as vitamins A, D, E, and K.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • See your doctor immediately if you have an allergic reaction or overdose after taking colestipol.

Dosage and Instructions for Use of Colestipol

Colestipol is only given based on doctor's advice. The following are common doses of colestipol for high cholesterol to lower bad cholesterol (LDL):

  • Tablet form

    The dose is 2 grams, 1-2 times a day, then increase the dose by 2 grams after 1-2 months of treatment. The maintenance dose is 2–16 grams per day, once a day or divided into several doses.

  • Powder form

    The dose is 5 grams, 1-2 times a day, then increase the dose by 5 grams after 1 month of treatment. The maximum dose is 30 grams per day, divided into 1-2 doses.

How to Take Colestipol Correctly

Follow the doctor's advice and read the information on the medicine package before taking colestipol. Do not reduce or increase the dose without consulting your doctor first.

Colestipol can be taken before or after meals. Try to take colestipol at the same time every day for maximum treatment.

Swallow colestipol tablets whole with the help of a glass of water. Do not chew or crush the tablet

Dissolve colestipol powder into drinks or food. This medicine should not be taken in dry form. Consume food or drink that has been mixed with medicine until it runs out, in order to get the right dose.

Swallow the colestipol solution immediately without gargling or keeping it in the mouth, because this medicine can damage teeth if left for too long.

If you are taking other medicines, take them at least 1 hour before or 4–6 hours after taking colestipol.

During treatment with colestipol, your doctor may ask you to do regular blood tests. Follow the examination schedule that has been determined by the doctor.

If you forget to take colestipol, it is recommended to take it immediately if the break with the next consumption schedule is not too close. If it's close, ignore it and don't double the dose.

Store colestipol in a dry place and avoid direct sunlight. Keep this medicine out of reach of children.

Colestipol Interaction with Other Drugs

Colestipol may inhibit the absorption of the following medicines when taken at the same time:

  • Folic Acid
  • Phosphate Supplements
  • Tetracycline
  • Penicillin G
  • Hydrochlorothiazide
  • Furosemide
  • Gemfibrozil
  • Fat soluble vitamins, such as vitamin D or A
  • Digoxin
  • Mycophenolic acid
  • Propranolol

Side Effects and Dangers of Colestipol

Some of the side effects that can occur after taking colestipol are:

  • stomach ache
  • stomach bloating
  • Constipation or diarrhea
  • Nausea or vomiting
  • Headache
  • Lost appetite
  • Blood stool or black stool
  • Easy bruising or unusual bleeding

Consult a doctor if the above side effects do not subside or are getting worse. You should also see a doctor immediately if you experience an allergic reaction to the drug after taking colestipol.