Omalizumab - Benefits, dosage and side effects

Table of contents:

Omalizumab - Benefits, dosage and side effects
Omalizumab - Benefits, dosage and side effects
Anonim

Omalizumab is a drug to treat asthma that has been diagnosed through allergy testing. This drug is known to reduce the frequency of recurrence of asthma attacks. Omalizimab is not intended for the treatment of acute asthma attacks or status asthmaticus

Omalizumab belongs to the monoclonal antibody group that works by inhibiting the body's natural substances, namely immunoglobulin E (IgE). By inhibiting this substance, asthma symptoms can subside. This drug is available in the form of an injection that will be given directly by a doctor at a hospital or he alth facility.

Omalizumab - Alodokter

Omalizumab trademark: Xolair

What is Omalizumab

Class Prescription drugs
Categories Monoclonal antibody
Benefits Treating asthma
Used by Adults and children
Omalizumab for pregnant and lactating women Category N: Not categorized yet.

Omalizumab is not known to be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Medicine form Inject

Warning Before Using Omalizumab

There are several things you should pay attention to before using omalizumab, including:

  • Tell your doctor about any allergies you have. Omalizumab should not be used by someone who is allergic to latex, pollen, or any of the ingredients in this medicine.
  • Tell your doctor if you have any symptoms of infection, such as fever, swollen lymph nodes, not feeling well, or if you have an infectious disease, including parasitic infections such as toxoplasmosis or malaria.
  • Tell your doctor if you have had a previous heart attack, severe allergic reaction, such as anaphylactic shock.
  • Tell your doctor if you have or have ever had a stroke or cancer.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking any other medicines, including supplements, or herbal products.
  • See your doctor immediately if you experience an overdose, allergic reaction to the drug, or more serious side effects after taking omalizumab.

Dosage and Instructions for Use Omalizumab

Omalizumab will be injected directly by a doctor or medical officer under the supervision of a doctor. The injection is done under the skin (subcutaneous/SC) The dose given depends on the patient's he alth condition and body response.

The following is the distribution of omalizumab doses based on the patient's condition, IgE levels, and age:

Condition: Asthma

  • Adults weighing 30–90 kg: 150–375 mg every 4 weeks, the dose is determined according to serum IgE levels.
  • Adults weighing >90–150 kg: 225–300 mg every 4 weeks, the dose is determined according to the serum IgE level.
  • Children: The dose is determined by the doctor according to the patient's condition.

Condition: Chronic idiopathic urticaria

  • Adults: 300 mg every 4 weeks
  • Children: The dose is determined by the doctor according to the patient's condition.

How to Use Omalizumab Correctly

Omalizumab injection will be given directly by a doctor or medical officer under the supervision of a doctor through an injection under the patient's skin. At the beginning of the administration of the drug, close monitoring is necessary, because this drug can cause a severe allergic reaction.

Follow your doctor's advice and advice if you are on treatment with omalizumab. Do not stop taking medication without consulting your doctor first.

Do the control according to the schedule given by the doctor. During treatment with omalizumab, you may be asked to have a skin allergy test, lung function test, or complete blood test.

Interaction of Omalizumab with Other Drugs

It is not known with certainty the drug interactions that can occur when omalizumab is used with other drugs. However, omalizumab can decrease the effectiveness of antiparasitic drugs.

To prevent unwanted drug interactions from occurring, be sure to tell your doctor if you are or will be taking any other medicines while taking omalizumab.

Side Effects and Dangers of Omalizumab

Omalizimab can cause an anaphylactic reaction, which can be characterized by shortness of breath due to narrowing of the airways (bronchospasm), hypotension, fainting, hives, or angioedema. Immediately see a doctor if you experience these symptoms.

Side effects that can occur after using omalizumab include:

  • bruising, swelling, pain, or irritation at the injection site
  • Headache or dizziness

Do an examination to the doctor if the above complaints do not subside or are actually getting worse. See a doctor immediately if you experience more serious side effects, such as:

  • severe chest pain, weakness on one side of the body, excessive sweating, visual disturbances, slurred speech, or confusion
  • Numbness or tingling in the arms or legs
  • Shortness of breath or coughing up blood
  • Fever, not feeling well, sore throat, or cough that doesn't go away

Popular topic