Risedronate - Benefits, dosage and side effects

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Risedronate - Benefits, dosage and side effects
Risedronate - Benefits, dosage and side effects

Risedronate or risedronic acid is a drug to prevent and treat postmenopausal osteoporosis. It is also used in the treatment of osteoporosis due to long-term corticosteroid use and Paget's disease

Risedronate belongs to the bisphosphonate group which works by means of the bone resorption process so as to prevent the loss of bone mass. That way, bone strength and density are maintained and the risk of fracture will be reduced.

Risedronate - Alodokter

Risedronate trademark: Actonel Once a-Week, Actonel Once a-Month, Osteonate Oaw, Ristonat

What is Risedronate

Class Prescription drugs
Categories Bisphosphonates
Benefits Prevent and treat postmenopausal osteoporosis, treat osteoporosis due to long-term use of corticosteroid drugs, and Paget's disease
Consumed by Adult
Risedronate for pregnant and lactating mothers Category C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women.

Drugs should only be used if the expected benefit outweighs the risk to the fetus.

Risedronate is not known whether it can be absorbed into breast milk or not. If you are breastfeeding, do not use this medication without telling your doctor.

Medicine form Tablets

Warning Before Consuming Risedronate

Risedronate should not be consumed carelessly and must be according to a doctor's prescription. Here are some things you should pay attention to before taking risedronate:

  • Tell your doctor about any allergies you have. Risenndronate should not be taken by someone who is allergic to this drug.
  • Tell your doctor if you have difficulty swallowing, cannot sit or stand for long periods of time, or are undergoing chemotherapy or radiotherapy.
  • Tell your doctor if you have or have had achalasia, low calcium levels, stomach ulcers, kidney disease, dental or oral disease, malabsorption, cancer, or blood disorders.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking any other medicines, including supplements, or herbal products.
  • Tell your doctor that you are taking risedronate and have not had any surgery or medical procedures, including dental surgery.
  • See your doctor immediately if you experience an allergic reaction to a drug, a serious side effect, or an overdose, after taking risedronate.

Dosage and Rules for Use of Risedronate

The dose of risedronate is determined based on the age, the patient's condition, and the body's response to the drug. The following are the dosages of risedronate for adults based on their intended use:

  • Aim: Prevent and treat postmenopausal osteoporosisThe dosage is 5 mg, once a day or 35 mg, once a week, or 150 mg, once a month.

  • Aim: Treating osteoporosis due to long-term use of corticosteroid drugsThe dosage is 5 mg per day

  • Purpose: Treating Paget's diseaseThe dose is 30 mg, once a day, for 2 months.

  • Aim: Increase bone mass in men with osteoporosisThe dose is 35 mg, once a week.

How to Consume Risedronate Correctly

Follow the doctor's advice and always read the instructions for use listed on the risedronate packaging. Do not increase or decrease the dose, and do not use the drug for more than the recommended time.

Risedronate tablets are taken in the morning on an empty stomach or at least 30 minutes before breakfast. Swallow the risedronate tablets whole with the help of a glass of water. Do not chew, split or crush the medicine.

To prevent irritation of the throat, take risedronate sitting or standing. Do not lie down and consume any food or drink for at least 30 minutes before taking the medicine.

While undergoing treatment with risedrone, you are also advised to always maintain dental hygiene and have regular dental check-ups with the doctor.

Make sure there is enough time between one dose and the next. Try to take risedronate at the same time every day for maximum treatment.

If you forget to take risedronate, take it immediately if the break with the next consumption schedule is not too close. If it's close, ignore it and don't double the dose.

Do the control according to the schedule given by the doctor, so that the condition and response to therapy can be monitored. Do not smoke or consume alcoholic beverages as this can increase bone loss and make the condition worse.

Store risedronate in a dry, closed place, and avoid exposure to direct sunlight. Keep medicine out of reach of children.

Risedronate Interaction with Other Drugs

There are several drug interaction effects that can occur when risedronate is used with certain drugs, including:

  • Decreased absorption of risedronate when used with antacids or mineral supplements containing calcium, aluminum, or magnesium
  • Increased risk of peptic ulcers and gastrointestinal bleeding when used with deferasirox or non-steroidal anti-inflammatory drugs, such as diclofenac or ibuprofen
  • Increased risk of low blood calcium levels (hypokalemia) when used with etelcalcetide

Side Effects and Dangers of Risedronate

Some of the common side effects that can occur after taking risedronate are:

  • Diarrhea
  • Constipation
  • Bloating or stomach ache
  • Headache
  • Muscle pain, joint pain, or bone pain

Consult a doctor if the above side effects do not subside or get worse. Immediately see a doctor if an allergic reaction occurs to the drug which can be characterized by the appearance of symptoms in the form of an itchy rash, swelling of the eyes and lips, or difficulty breathing.

In addition, you should also go to the doctor immediately if you experience more serious side effects, such as:

  • Muscle pain, joint pain, hip pain, severe
  • Pain or swelling in the jaw or sudden loss of teeth
  • Ear pain, discharge from the ear, and infection of the earbone
  • Muscle cramps, muscle stiffness, or tingling
  • severe stomach pain, bloody or black stools, difficulty swallowing, or painful swallowing

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