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Tiotropium - Benefits, dosage and side effects

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Tiotropium - Benefits, dosage and side effects
Tiotropium - Benefits, dosage and side effects

Tiotropium is a drug to control and prevent the recurrence of symptoms of narrowing of the airways (bronchospasm) due to chronic obstructive pulmonary disease or COPD. Please note that this drug cannot be used to relieve sudden attacks of bronchospasm

Tiotropium is an anticholinergic bronchodilator. This drug works by relaxing the muscles of the respiratory tract. That way the respiratory tract can widen and air can flow more smoothly.

Tiotropium - Alodokter

When combined with inhaled corticosteroids (ICS) or long-acting beta agonists (LABA), these drugs are also used to relieve and prevent asthma symptoms.

Tiotropium trademarks: Spiriva, Spiriva Respimat, Spiolto Respimat

What is Tiotropium

Class Prescription drugs
Categories Anticholinergic bronchodilators
Benefits Control and prevent symptoms of wheezing, coughing, and shortness of breath, due to asthma or COPD
Used by Adults and children
Tiotropium for pregnant and lactating women Category B: Animal studies have not shown any risk to the fetus, but there are no controlled studies in pregnant women. Tiotropium is not known to be absorbed into breast milk or not. If you are breastfeeding, please consult your doctor before using this medicine.
Medicine form Inhalers

Warning Before Using Tiotropium

Tiotropium should only be used according to a doctor's prescription. Before using tiotropium there are several things you should pay attention to, namely:

  • Tell your doctor about any allergies you have. Tiotropium should not be given to patients who are allergic to this drug, atropine, or ipratropium.
  • Tell your doctor if you have or have had glaucoma, enlarged prostate gland, heart rhythm disturbances (arrhythmias), or kidney disease.
  • Tell your doctor if you are taking certain medications, supplements or herbal products.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor that you are taking tiotropium prior to any surgery, including dental surgery.
  • Do regular check-ups and checkups as recommended by your doctor while you are taking tiotropium.
  • Do not drive a vehicle or do activities that require alertness after taking tiotropium, as this drug can cause dizziness.
  • See your doctor immediately if you have an allergic reaction, serious side effects, or overdose after taking tiotropium.

Dosage and Instructions for Use of Tiotropium

Tiotropium dose will be adjusted according to the patient's condition and age. The following is a general dosage of tiotropium based on its intended use:

Purpose: Relieve or prevent recurrence of constriction of the respiratory tract (bronchospasm) caused by COPD

Medication form: Inhaler

  • Adult: Two puffs equals 5 mcg per day.

Goal: Preventing asthma relapse

Medication form: Inhaler

  • Adults and children over 6 years: Two puffs equals 2.5 mcg per day.

How to Use Tiotropium Correctly

Follow the doctor's advice and read the information on the medicine package before using tiotropium. Do not increase or decrease the dose without consulting your doctor first.

Tiotropium in the form of an inhaler that is used for the first time needs to be sprayed into the air 3 times, before being inhaled according to the doctor's recommended dose.

Hold the inhaler upright and rotate it in the direction of the arrow until it clicks. Exhale slowly, then insert the inhaler mouthpiece between your teeth and close your mouth.

Start breathing through your mouth slowly while pressing the dose button down to inhale the medicine. Hold your breath and remove the inhaler from your mouth, then exhale into the air after at least 5 seconds have passed. Do this one more time, because the inhaler is usually sprayed 2 times at almost the same time.

If you need to use another inhaler, wait for 1 minute to pass before using the medicine. After using the medicine, rinse your mouth with water to prevent dry mouth and throat irritation.

If you forget to use tiotropium, do it immediately if the break with the next schedule of use is not too close. If it's close, ignore it and don't double the dose.

Keep tiotropium in its package in a dry and cool place. Keep the drug away from direct sunlight. Keep medicine out of reach of children.

Interaction of Tiotropium with Other Drugs

The following are the effects of drug interactions that can occur if tiotropium is used with certain drugs:

  • Increased risk of serious side effects when used with umeclidinium bromide or inhaled vilanterol
  • Increased risk of bowel movement disorders when used with glucagon or pramlintide
  • Enhanced anticholinergic effect of tiotropium when used with revefenacin
  • Increased risk of side effects, such as drowsiness, dry mouth, or blurred vision, when used with antihistamine drugs, such as brompheniramine, hydroxyzine, or chlorpheniramine

Side Effects and Dangers of Tiotropium

Side effects that can occur after using this drug are:

  • Dry mouth
  • Constipation or constipation
  • Blurred vision
  • Vomiting or stomach pain
  • flu symptoms, such as stuffy nose
  • White rash that hurts in the mouth

Consult a doctor if the side effects mentioned above do not subside or are getting worse. Go to the doctor immediately if you experience a drug allergic reaction or serious side effects, such as:

  • Chest pain or fast heart rate
  • Voice changed
  • Difficult and painful urination
  • Headache, fever, or signs of infection, including sore throat
  • Red eyes, blurred vision that doesn't improve, eye pain, or seeing halos (halos)

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