Selegiline - Benefits, dosage and side effects

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Selegiline - Benefits, dosage and side effects
Selegiline - Benefits, dosage and side effects

Selegiline is an adjunct medication used to control the symptoms of Parkinson's disease. This medication will be prescribed with other Parkinson's medications, such as levodopa

Selegiline works by increasing the amount of the hormone dopamine, which is a hormone that controls movement. Although it can be used as an adjunct therapy to control the symptoms of Parkinson's disease, it is not a cure for this condition.

Selegiline - alodokter

Selegiline trademark: Jumex

What is Selegiline

Class MAOIs
Categories Prescription drugs
Benefits Controlling complaints in Parkinson's disease
Used by Adults and seniors
Selegiline for pregnant and lactating mothers Category C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus.

It is not known whether selegiline can be absorbed in breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Shapes Tablets

Warning Before Consuming Selegiline

Selegiline should not be used carelessly. Follow the doctor's recommendations while undergoing treatment with this medicine. Before taking selegiline, you need to pay attention to the following things:

  • Do not take selegiline if you have a history of allergies to this drug.
  • Do not take selegiline if you are taking other antidepressants, including fluoxetine.
  • Do not eat foods that are high in tyramine, such as beef and soybeans, while on treatment with selegiline.
  • Do not do activities that require high alertness, such as driving a vehicle, after taking selegiline, because this drug can make you dizzy.
  • Tell your doctor if you are or have ever taken any medications, vitamin supplements, or herbal products.
  • Tell your doctor if you have liver disease, hypertension, kidney disease, phenylketonuria.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • If there is an allergic reaction to the drug or an overdose after taking selegiline, see a doctor immediately.

Dosage and Rules for Use of Selegiline

Seregiline dose is determined based on the age and condition of the patient. The following are the dosages of selegiline based on their intended use:

  • Treatment of Parkinson's disease in adults

    Dose: 5 mg, 2 times a dayMaximum dose: 10 mg

  • Treatment of Parkinson's disease in the elderly

    Dose: 5 mg, 2 times a dayMaximum dose: 10 mg

Selegiline can also be used to treat depression. The type of selegiline preparation used to treat depression is a patch (patch).

How to Consume Selegiline Correctly

When taking selegiline, follow the doctor's advice and read the instructions on the medicine package. Selegiline can be consumed in the morning and afternoon.

Make sure you always take selegiline at the same time every day to get maximum results.

If you forget to take your medicine, take it as soon as you remember if it is not too close to the next scheduled time to take your medicine. If it is close, ignore the missed dose and do not double the next dose.

Don't stop taking selegiline without a doctor's advice. While using this drug, do regular check-ups with your doctor so that your he alth condition can be continuously monitored.

Keep selegiline in a tightly closed container. Make sure the container is out of reach of children. Store well at room temperature and make sure not to store in a place where the temperature is too hot or in a humid place.

Selegiline Interaction with Other Drugs

Consuming selegiline with other drugs can cause interaction effects in the form of:

  • Increased risk of hypertension if used with amphetamines, rasagiline, bupropion, and clonazepam
  • Increased risk of serotonin syndrome if used with antidepressant drugs, such as duloxetine, 5-hydroxytryptophan, escitalopram, and meperidine
  • Increased risk of respiratory distress and hypotension if used with opioid drugs
  • Increased side effects of levodopa

Selegiline can also increase the risk of dangerous increases in blood pressure when taken with foods or drinks that contain tyramine, such as soy, dried meat, or mushroom extracts.

Side Effects and Dangers of Selegiline

There are some minor side effects that may occur after taking selegiline, including:

  • Dizzy
  • Dry mouth
  • stomach ache
  • Difficulty swallowing
  • Sleepy

Consult a doctor if the above side effects occur for a long time and continuously. In addition to the side effects above, selegiline can cause more serious side effects and require examination by a doctor, such as:

  • Severe headache
  • chest pain
  • Heart pounding
  • Sweating
  • Nausea and vomiting
  • Neck stiff or sore
  • Uncontrollable body movements
  • Hallucinations
  • Difficulty breathing

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