Aspirin - Benefits, dosage and side effects

Aspirin is a drug to relieve pain, fever, and inflammation. In addition, the drug, also known as acetylsalicylic acid, is also used to prevent blood clots from forming, thereby reducing the risk of heart attack or stroke in people with cardiovascular disease

Aspirin is a non-steroidal anti-inflammatory drug that works to prevent the formation of prostaglandins through the COX-1 inhibitor pathway. In addition, this drug can also work to prevent the formation of blood clots (antiplatelet).

Although it can be used to relieve fever and inflammation, giving aspirin to children who have the flu, fever, or chickenpox, is often associated with the risk of developing Reye's syndrome. Do not use this drug carelessly without the direction and advice of a doctor.

Aspirin trademarks: Acetylsalicylic Acid, Apstor, Ascardia, Aspilets, Astika, Bodrexin, Cardio Aspirin, Cartylo, Contrexyn, Coplavix, Pharmasal, Gramasal, Inzana, Miniaspi 80, Naspro, Nogren, Nospirinal, Novosta, Thrombo Aspilets

What Is Aspirin

Class	Prescription and over-the-counter drugs
Categories	Non-steroidal anti-inflammatory drugs (NSAIDs) and antiplatelets.
Benefits	Relieves pain, fever, inflammation and prevents the formation of blood clots.
Consumed by	Adult
Aspirin for pregnant and lactating women	Category C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus. NSAID drugs should not be used when gestational age is more than 20 weeks. Aspirin can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first.
Medicine form	Tablets

Warning Before Taking Aspirin

There are several things you should pay attention to before using aspirin, including:

• Tell your doctor about any allergies you have. Aspirin should not be given to patients who are allergic to this drug.
• Tell your doctor if you have asthma, gastrointestinal bleeding, or a blood clotting disorder, such as hemophilia or low levels of vitamin K.
• Tell your doctor if you have or have ever had liver disease, kidney disease, stomach ulcers, stomach ulcers, gout, hypertension, nasal polyps, or heart disease, including heart failure.
• Do not give aspirin to children without consulting their doctor first, because its use in children can increase the risk of Reye's syndrome.
• Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
• Tell your doctor if you are taking certain medications, supplements or herbal products.
• See your doctor immediately if you experience an allergic drug reaction, overdose, or serious side effects after using Aspirin.

Dosage and Instructions for Use of Aspirin

The following are aspirin doses for adults based on the condition to be treated:

• Condition: Fever or painInitial dose 300–900 mg, dose may be repeated after 4–6 hours if needed. The maximum dose is 4,000 mg per day.

• Conditions: Stroke, angina pectoris, heart attackFor the prevention of these conditions, the dose is 150–300 mg

• Condition: Rheumatic diseaseFor acute rheumatic disorders, the dose is 4,000–8,000 mg per day, divided into several doses. Meanwhile, for chronic conditions the dose is 5,400 mg per day, divided into several consumption doses.

• Condition: Prevention of cardiovascular disease in high-risk patientsFor long-term prevention, the dose is 75–150 mg once daily. For short-term prevention, the dose is 150–300 mg per day.

How to Take Aspirin Correctly

Always follow the doctor's instructions and read the information on the medicine package before taking aspirin.

Aspirin is taken after meals. Swallow the aspirin tablet whole with the help of a full glass of water. Do not crush, split, or chew aspirin tablets as this can increase the risk of side effects. Do not lie down immediately after taking the medicine. Wait up to 10 minutes, so you don't get a stomach ache.

Take aspirin regularly. Do not start or stop taking medication or increase or decrease the dose of medication without consulting your doctor first.

If you forget to take Aspirin tablets, take them as soon as you remember if the distance to the next consumption schedule is not too close. If it's close, ignore it and don't double the dose.

Store Aspirin in a dry place, away from direct sunlight, and at room temperature. Keep this medicine out of reach of children.

Interaction of Aspirin with Other Drugs

There are several interaction effects that can occur if aspirin is used with other drugs, including:

• Increased risk of bleeding or ulcers in the digestive tract when used with corticosteroids or other NSAIDs, such as ibuprofen
• Increased risk of damage to blood cells when used with methotrexate
• Increased risk of bleeding if used with other blood thinners, such as heparin, warfarin, phenindione, clopidogrel, or dipyridamole
• Increased risk of acidosis and damage to the central nervous system when used with acetazolamide
• Increased risk of low blood sugar (hypoglycemia) if used with sulfonylurea drugs
• Reduced blood levels of phenytoin, lithium, digoxin, or valproate
• Reduced effect of probenecid or sulfinpyrazone

Side Effects and Dangers of Aspirin

The following are some of the side effects that can occur after taking aspirin:

• Stomach pain or burning and burning sensation in the chest (Heartburn)
• Vomiting or nausea

Consult your doctor if these side effects don't get better or get worse. See your doctor immediately if you experience an allergic drug reaction or serious side effects, such as:

• Easy bruising, nosebleeds, or bleeding gums
• Lost appetite
• Dark urine, jaundice, or unusual tiredness
• Gastrointestinal bleeding which can be characterized by very severe abdominal pain, black vomit, or bloody stools
• Infrequent urination or very little urine output